| ORIGINAL HYPOTHESIS |
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| Year : 2015 | Volume
: 6
| Issue : 1 | Page : 6-9 |
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Possible mechanisms of lack of dentin bridge formation in response to calcium hydroxide in primary teeth
GR Ravi1, RV Subramanyam2
1 Department of Pedodontics and Preventive Dentistry, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Krishna District, Andhra Pradesh, India
2 Department of Oral and Maxillofacial Pathology, Anil Neerukonda Institute of Dental Sciences, Vishakapatnam, Andhra Pradesh, India
Correspondence Address:
G R Ravi
Department of Pedodontics and Preventive Dentistry, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences Chinnaoutpalli, Gannavaram, Krishna - 521 286, Andhra Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2155-8213.150863
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Introduction: The usage of Calcium hydroxide (CaOH2) has wide applications due to the property of osteo-inductive, protective, and antibacterial actions. However, it is not used in primary teeth, as it fails to form reparative dentin and the exact mechanism has not been explained. The hypothesis: The authors propose an explanation that lack of dentin bridge formation in response to (CaOH2) in primary teeth could be multifactorial: inability of the deciduous stem cells to generate complete dentin-pulp-like tissue; the absence of calcium-magnesium-dependent adenosine triphosphatase (Ca-Mg ATPase) in the odontoblasts; the pre-existing predilection of deciduous dentine pulp to form odontoclasts; the solubility of (CaOH2). Evaluation of the hypothesis: The hypothesis discusses the innate traits of the deciduous stem cells that lack the ability to form the dentin bridge, the absence of Ca-Mg ATPase enzyme and increased solubility of (CaOH2) together fail to stimulate the odontoblasts. Alternatively, pre-existing progenitor cells with proclivity to change into odontoclasts may cause internal resorption and hamper formation of reparative dentin. |
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