Search Article 
Advanced search 
Official publication of the American Biodontics Society and the Center for Research and Education in Technology
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2018  |  Volume : 9  |  Issue : 4  |  Page : 96-100

Is Systemic (Interstitial Fluid) Acidosis an Initial Event in the Etiopathogenesis of Dental Caries? A Hypothesis

Department of Oral and Maxillofacial Pathology and Microbiology, D .Y. Patil deemed to be University, School of Dentistry Sector -7, Nerul Navi Mumbai, Maharashtra, India

Correspondence Address:
Sandhya Tamgadge
Department of Oral & Maxillofacial Pathology and Microbiology, Grace-C, 802, Vasant Oscar, L.B.S Marg, Mulund West, Mumbai, Maharashtra, 400706
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/denthyp.denthyp_72_18

Rights and Permissions

Introduction: Dental caries is a microbial disease which affects retentive areas of the teeth. It has shown significant increase in incidence and prevalence in modern population. Various theories have been postulated in an attempt to explain the etiopathogenesis of dental caries. Despite their popularity, there are many questions which various theories haven’t been able to answer. And still there is no definite cure for dental caries. Consequently, in most cases the process can’t be reversed. Therefore, to tackle this issue other risk factors involved in the etiopathogenesis need to be explored. The Hypothesis: It could be suggested that there might be additional systemic factors, e.g. systemic acidosis, in pathogenesis of dental caries, in addition to proven localized causative factors. Evaluation of the Hypothesis: Various hypotheses have been discussed, on the basis of histopathology, and various research articles. The demineralization of bone osteoporosis and tooth demineralization of dental caries have been correlated to evaluate the hypothesis. Few parameters have been added in the proven local factors of etiopathogenesis of dental caries.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded559    
    Comments [Add]    
    Cited by others 1    

Recommend this journal