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Effect of Amoxicillin and Azithromycin Suspensions on Microhardness of Sliver Reinforced and Nano Resin-Modified Glass Ionomers: An In Vitro Study
Zainab R Hasan1, Noor R Al-Hasani2, Maha Abdulkareem Mahmood3, Ali I Ibrahim4
1 Pedodontics Department, College of Dentistry, University of Baghdad, Baghdad, Iraq
2 Department of Basic Sciences, College of Dentistry, University of Baghdad, Baghdad, Iraq
3 Pedodontics Department, College of Dentistry, Al-Mustansiriya University, Baghdad, Iraq
4 Department of Orthodontics, College of Dentistry, University of Baghdad, Baghdad; Centre for Oral, Clinical and Translational Sciences, Faculty of Dentistry, Oral & Craniofacial Sciences, King’s College London, London, UK, Iraq
Correspondence Address:
Zainab R Hasan
Pedodontics Department, College of Dentistry, University of Baghdad, Baghdad
Iraq
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/denthyp.denthyp_149_22
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Introduction: We aimed to examine the effect of amoxicillin and azithromycin suspensions on the microhardness of sliver-reinforced glass ionomer and nano-resin modified glass ionomer (GI). Method: Thirty discs (2 mm height x 4 mm diameter) of each type of GI were prepared, which were randomly assigned to amoxicillin, azithromycin, and artificial saliva groups. Microhardness was evaluated by Vickers hardness test before and after three immersion cycles. Results: The overall model (P < 0.001), before/after intervention (P < 0.001), intervention group (type of antibiotic) (P = 0.013), and type of glass ionomer (P < 0.001) showed significant differences among study groups (P < 0.001). Post hoc test showed only non-significant before/after difference for Azithromycin and artificial saliva (control) groups regarding nano resin-modified GI. Conclusion: We found significant microhardness loss for sliver reinforced GI in comparison to nano resin-modified GI after the immersion cycles. Yet, sliver reinforced GI would have higher level of microhardness than nano resin-modified GI after the immersion cycles. Longer time studies are required to assess trend of microhardness loss.
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